Population-Based Study of First Onset and Chronicity in Major Depressive Disorder

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Population-based study of first onset and chronicity in major depressive disorder.

CONTEXT There are no studies of the natural history of major depressive disorder that lack prevalence and clinic biases. OBJECTIVES To estimate risk factors for first lifetime onset and parameters of chronicity following the first episode, including duration, recovery, and recurrence, and to search for predictors of each parameter. DESIGN Prospective population-based cohort study with 23 ye...

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Objective: Similarities and differences among mood disorders can help psychiatrics in their exact diagnosis and more effective treatments. Therefore, the current research sought to identify differences between patients with bipolar disorder, major depressive disorder, and nonclinical group in emotional schemas. Methods: The present research was a cross-sectional study. The research sample cons...

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Background:  Study of personality can help to explanation of pathology in mental disorders. The aim of this study was to examine major depressive disorder (MDD) based on revised- reinforcement sensitivity theory (r-RST). Materials and Methods: Forty-five patients with MDD along with 45 healthy individuals as a control group participated in the present study. Following the informed consent f...

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Predictors of first lifetime onset of major depressive disorder in young adulthood.

The first onset of major depressive disorder (MDD) most frequently occurs in young adulthood. However, few studies have examined predictors of first lifetime MDD during this high-risk period. The present study examined a broad range of demographic, clinical, and psychosocial variables as prospective predictors of first onset of MDD in a large community sample of young adults (N = 502) from the ...

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ژورنال

عنوان ژورنال: Archives of General Psychiatry

سال: 2008

ISSN: 0003-990X

DOI: 10.1001/archpsyc.65.5.513